PEN (rat)

CAS No. 569364-13-2

PEN (rat)( —— )

Catalog No. M30583 CAS No. 569364-13-2

Endogenous peptide GPR83 agonist. ProSAAS-derived neuropeptide.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
100MG Get Quote Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote

Biological Information

  • Product Name
    PEN (rat)
  • Note
    Research use only, not for human use.
  • Brief Description
    Endogenous peptide GPR83 agonist. ProSAAS-derived neuropeptide.
  • Description
    Endogenous peptide GPR83 agonist. ProSAAS-derived neuropeptide.
  • In Vitro
    Mouse PEN (mPEN) and rat PEN (rPEN) only differ by one residue at the N-terminal end, whereas human PEN (hPEN) is more divergent and has the sequence PEG instead of PEN.PEN binds and activates a GPCR in the brain.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    GRK (GPCRK)
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    569364-13-2
  • Formula Weight
    2301.62
  • Molecular Formula
    C102H169N27O33
  • Purity
    >98% (HPLC)
  • Solubility
    PBS (pH 7.4):1 mg/mL
  • SMILES
    [H]N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Gomes et al (2016) Identification of GPR83 as the receptor for the neuroendocrine peptide PEN. Sci.Signal. 9 ra43 PMID:
molnova catalog
related products
  • Compound 101

    Compound 101 (GRK2 inhibitor 101, Takeda compound 101, Cmpd101)?is a novel membrane-permeable, small-molecule inhibitor of GRK2 and GRK3.

  • GRK6-IN-1

    GRK6-IN-1 (compound 18) is a potent inhibitor of G protein-coupled receptor kinase 6 (GRK6) with an IC50 of 120 nM, and has potential for study in multiple myeloma.

  • GSK270822A

    GSK270822A is a selective ROCK1 inhibitor. GSK270822A exhibits IC50 of 9nM, 1100nM, 1550nM for ROCK1, RSK1, p70S6K, respectively.